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The common drivers: A weak or loose LES A hiatal hernia (part of the stomach pushing up through the diaphragm) Eating large meals, especially within three hours of bed Excess abdominal weight pressing on the stomach Smoking (which relaxes the LES) Pregnancy Certain medications, including some blood pressure drugs and asthma inhalers I tell patients this all the time: if you have reflux and youve never had a proper workup, youre treating a symptom and ignoring the engine

References Fleming A: On a remarkable bacteriolytic element found in tissues and secretions

"The effects of human growth hormone and its lipolytic fragment (AOD9604) on lipid metabolism following chronic treatment in obese mice and beta(3)-AR knock-out mice." Endocrinology 142.12 (2001): 5182-5189

To support your weight loss efforts, the Bethany Health Services team can recommend strategies like: Nutrition counseling Daily exercise programs Weight loss medications Hormone therapy The team also has extensive experience addressing mental health disorders like anxiety and depression that can contribute to weight gain or make weight loss difficult

Antioxid Redox Signal (2013) 19:185560